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Efficient DNA double-strand break formation at single or multiple defined sites in the Saccharomyces cerevisiae genome

DNA double-strand breaks (DSBs) are common genome lesions that threaten genome stability and cell survival. Cells use sophisticated repair machineries to detect and heal DSBs. To study DSB repair pathways and associated factors, inducible site-specific endonucleases have proven to be fundamental too...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gnügge, Robert, Symington, Lorraine S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672422/
https://ncbi.nlm.nih.gov/pubmed/33053188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa833
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