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Why do some asthma patients respond poorly to glucocorticoid therapy?

Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma. They bind intracellular glucocorticoid receptors to trigger increased expression of anti-inflammatory genes and suppression of pro-inflammatory gene activation in asthmatic airways. In the majority of asth...

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Detalles Bibliográficos
Publicado en:Pharmacol Res
Main Authors: Henderson, Ishbel, Caiazzo, Elisabetta, McSharry, Charles, Guzik, Tomasz J., Maffia, Pasquale
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672256/
https://ncbi.nlm.nih.gov/pubmed/32911071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105189
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