TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification

BACKGROUND: Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies. Some existing bioinformatics methods, such as MHCflurr...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Tang, Yunxia, Wang, Yu, Wang, Jiaqian, Li, Miao, Peng, Linmin, Wei, Guochao, Zhang, Yixing, Li, Jin, Gao, Zhibo
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672179/
https://ncbi.nlm.nih.gov/pubmed/33208106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03869-9
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