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Endothelial cell apicobasal polarity coordinates distinct responses to luminally versus abluminally delivered TNF-α in a microvascular mimetic

Endothelial cells (ECs) are an active component of the immune system and interact directly with inflammatory cytokines. While ECs are known to be polarized cells, the potential role of apicobasal polarity in response to inflammatory mediators has been scarcely studied. Acute inflammation is vital in...

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Detalles Bibliográficos
Publicado en:Integr Biol (Camb)
Main Authors: Salminen, Alec T, Tithof, Jeffrey, Izhiman, Yara, Masters, Elysia A, McCloskey, Molly C, Gaborski, Thomas R, Kelley, Douglas H, Pietropaoli, Anthony P, Waugh, Richard E, McGrath, James L
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671990/
https://ncbi.nlm.nih.gov/pubmed/33164044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intbio/zyaa022
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