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Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain
The Sigma-1 receptor (σ(1)R) is highly expressed in the primary sensory neurons (PSNs) that are the critical site of initiation and maintenance of pain following peripheral nerve injury. By immunoblot and immunohistochemistry, we observed increased expression of both σ(1)R and σ1R-binding immunoglob...
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| Pubblicato in: | Gene Ther |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2022
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7671947/ https://ncbi.nlm.nih.gov/pubmed/32424233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-020-0157-5 |
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