Neisseria meningitidis Urethritis Outbreak Isolates Express a Novel Factor H Binding Protein Variant That Is a Potential Target of Group B-Directed Meningococcal (MenB) Vaccines

Factor H binding protein (FHbp) is an important Neisseria meningitidis virulence factor that binds a negative regulator of the alternative complement pathway, human factor H (FH). Binding of FH increases meningococcal resistance to complement-mediated killing. FHbp also is reported to prevent intera...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Tzeng, Yih-Ling, Giuntini, Serena, Berman, Zachary, Sannigrahi, Soma, Granoff, Dan M., Stephens, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671903/
https://ncbi.nlm.nih.gov/pubmed/32958529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00462-20
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