Preclinical Efficacy and Safety of VEGF-Grab, a Novel Anti-VEGF Drug, and Its Comparison to Aflibercept

PURPOSE: VEGF-Grab is a novel anti-vascular endothelial growth factor (VEGF) candidate drug with higher affinity to both VEGF and placental growth factor (PlGF) compared to aflibercept. We investigated the preclinical efficacy of VEGF-Grab for ophthalmic therapy and compared it to that of aflibercep...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Hong, Hye Kyoung, Park, Young Joo, Kim, Duk Ki, Ryoo, Na-Kyung, Ko, You-Jin, Park, Kyu Hyung, Kim, Ho Min, Woo, Se Joon
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
Assuntos:
Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671872/
https://ncbi.nlm.nih.gov/pubmed/33196778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.13.22
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