Effect of Pioglitazone on Perihematomal Edema in Intracerebral Hemorrhage Mouse Model by Regulating NLRP3 Expression and Energy Metabolism

OBJECTIVE: Cerebral edema is the predominant mechanism of secondary inflammation after intracerebral hemorrhage (ICH). Pioglitazone, peroxisome proliferator-activated receptor gamma agonist has been shown to play a role in regulation of central nervous system inflammation. Here, we examined the phar...

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Bibliographic Details
Published in:J Korean Neurosurg Soc
Main Authors: Kim, Hoon, Lee, Jung Eun, Yoo, Hyun Ju, Sung, Jae Hoon, Yang, Seung Ho
Format: Artigo
Language:Inglês
Published: Korean Neurosurgical Society 2020
Subjects:
Laboratory Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671775/
https://ncbi.nlm.nih.gov/pubmed/33105536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3340/jkns.2020.0056
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