SON and SRRM2 are essential for nuclear speckle formation

Nuclear speckles (NS) are among the most prominent biomolecular condensates. Despite their prevalence, research on the function of NS is virtually restricted to colocalization analyses, since an organizing core, without which NS cannot form, remains unidentified. The monoclonal antibody SC35, raised...

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Pubblicato in:eLife
Autori principali: Ilik, İbrahim Avşar, Malszycki, Michal, Lübke, Anna Katharina, Schade, Claudia, Meierhofer, David, Aktaş, Tuğçe
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Biochemistry and Chemical Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671692/
https://ncbi.nlm.nih.gov/pubmed/33095160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60579
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