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Losses of human disease-associated genes in placental mammals
We systematically investigate whether losses of human disease-associated genes occurred in other mammals during evolution. We first show that genes lost in any of 62 non-human mammals generally have a lower degree of pleiotropy, and are highly depleted in essential and disease-associated genes. Desp...
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| Publicat a: | NAR Genom Bioinform |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7671337/ https://ncbi.nlm.nih.gov/pubmed/33575564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqz012 |
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