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Follistatin treatment modifies DNA methylation of the CDX2 gene in bovine preimplantation embryos

CDX2 plays a crucial role in the formation and maintenance of the trophectoderm epithelium in preimplantation embryos. Follistatin supplementation during the first 72 hr of in vitro culture triggers a significant increase in blastocyst rates, CDX2 expression, and trophectoderm cell numbers. However,...

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Bibliografske podrobnosti
izdano v:Mol Reprod Dev
Main Authors: Ashry, Mohamed, Rajput, Sandeep K., Folger, Joseph K., Yang, Chunyan, Knott, Jason G., Smith, George W.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670970/
https://ncbi.nlm.nih.gov/pubmed/32776625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.23409
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