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Repurposing Fostamatinib to Combat SARS-CoV-2-Induced Acute Lung Injury

A screen by Kost-Alimova et al.(1) suggests that the FDA-approved SYK inhibitor fostamatinib inhibits MUC1 in the respiratory tract and has the potential to treat serious outcomes of coronavirus COVID-19, including acute respiratory distress syndrome (ARDS) and acute lung injury (ALI).

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep Med
Prif Awduron: Tabassum, Neha, Zhang, Hua, Stebbing, Justin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670931/
https://ncbi.nlm.nih.gov/pubmed/33225317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100145
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