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HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

BACKGROUND: Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC). Gene copy number variation (CNV) could be detected in these patients in liquid biopsy and in cancer cells. METHODS:...

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Dettagli Bibliografici
Pubblicato in:BMC Gastroenterol
Autori principali: Grenda, Anna, Wojas-Krawczyk, Kamila, Skoczylas, Tomasz, Krawczyk, Paweł, Sierocińska-Sawa, Jadwiga, Wallner, Grzegorz, Milanowski, Janusz
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670771/
https://ncbi.nlm.nih.gov/pubmed/33198632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-020-01531-5
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