Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq

BACKGROUND: Intra-articular glucocorticoid (GC) injections are widely used as a symptomatic treatment for osteoarthritis (OA). However, there are also concerns about their potentially harmful effects, and their detailed effects on chondrocyte phenotype remain poorly understood. METHODS: We studied t...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Pemmari, Antti, Leppänen, Tiina, Hämäläinen, Mari, Moilanen, Teemu, Vuolteenaho, Katriina, Moilanen, Eeva
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670667/
https://ncbi.nlm.nih.gov/pubmed/33203447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02289-7
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