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Intravenous administration of sodium propionate induces antidepressant or prodepressant effect in a dose dependent manner
Propionate has been reported to exert antidepressant effects, but high-dose propionate may induce autism-like symptoms in experimental animals through induction of dysbiosis of neurotransmitters. The bi-directional effects of propionate seem to be dose-dependent. However, due to the pathological dis...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7670463/ https://ncbi.nlm.nih.gov/pubmed/33199803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77085-z |
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