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Intravenous administration of sodium propionate induces antidepressant or prodepressant effect in a dose dependent manner

Propionate has been reported to exert antidepressant effects, but high-dose propionate may induce autism-like symptoms in experimental animals through induction of dysbiosis of neurotransmitters. The bi-directional effects of propionate seem to be dose-dependent. However, due to the pathological dis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hao, Chunyan, Gao, Zefeng, Liu, XianJun, Rong, Zhijiang, Jia, Jingjing, Kang, Kaiqi, Guo, Weiwei, Li, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670463/
https://ncbi.nlm.nih.gov/pubmed/33199803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77085-z
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