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Tetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability

This study aimed to investigate the influence of chronic ischemia on nitric oxide biosynthesis in the bladder and the effect of administering tetrahydrobiopterin (BH4), a cofactor for endothelial nitric oxide synthase (eNOS), on chronic ischemia-related lower urinary tract dysfunction (LUTD). This s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Akaihata, Hidenori, Hata, Junya, Tanji, Ryo, Honda-Takinami, Ruriko, Matsuoka, Kanako, Sato, Yuichi, Kataoka, Masao, Ogawa, Soichiro, Kojima, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670448/
https://ncbi.nlm.nih.gov/pubmed/33199757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76948-9
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