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Predictive design of sigma factor-specific promoters

To engineer synthetic gene circuits, molecular building blocks are developed which can modulate gene expression without interference, mutually or with the host’s cell machinery. As the complexity of gene circuits increases, automated design tools and tailored building blocks to ensure perfect tuning...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Van Brempt, Maarten, Clauwaert, Jim, Mey, Friederike, Stock, Michiel, Maertens, Jo, Waegeman, Willem, De Mey, Marjan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670410/
https://ncbi.nlm.nih.gov/pubmed/33199691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19446-w
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