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Interchangeability of Biosimilars: What Level of Clinical Evidence is Needed to Support the Interchangeability Designation in the United States?

A biosimilar is a biologic drug that is “highly similar to a reference (originator) product, with no clinically meaningful differences between the two products in safety, purity, and potency”. Regulatory approval of a biosimilar is based on analytical, structural, and functional comparisons with the...

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Dettagli Bibliografici
Pubblicato in:BioDrugs
Autori principali: Alvarez, Daniel F., Wolbink, Gertjan, Cronenberger, Carol, Orazem, John, Kay, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669758/
https://ncbi.nlm.nih.gov/pubmed/32990892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-020-00446-7
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