Glycation of HDL blunts its anti-inflammatory and cholesterol efflux capacities in vitro, but has no effect in poorly controlled type 1 diabetes subjects

BACKGROUND: High-density lipoproteins (HDL) modified by glycation have been reported to be dysfunctional. Little is known regarding the anti-inflammatory effects on adipocytes of glycated HDL. AIMS: We tested whether modification of HDL in vitro by glycolaldehyde (GAD), malondialdehyde (MDA) or gluc...

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Vydáno v:J Diabetes Complications
Hlavní autoři: Kjerulf, Diego Gomes, Wang, Shari, Omer, Mohamed, Pathak, Asha, Subramanian, Savitha, Han, Chang Yeop, Tang, Chongren, den Hartigh, Laura J., Shao, Baohai, Chait, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669727/
https://ncbi.nlm.nih.gov/pubmed/32900591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2020.107693
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