Protein arginine methyltransferase 5 promotes pICln-dependent androgen receptor transcription in castration-resistant prostate cancer

The majority of advanced prostate cancer therapies aim to inhibit androgen receptor (AR) signaling. However, AR reactivation inevitably drives disease progression to castration-resistant prostate cancer (CRPC). Here we demonstrate that protein arginine methyltransferase 5 (PRMT5) functions as an epi...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Beketova, Elena, Fang, Shuyi, Owens, Jake L, Liu, Sheng, Chen, Xufeng, Zhang, Qingfu, Asberry, Andrew M., Deng, Xuehong, Malola, Jonathan, Huang, Jiaoti, Li, Chenglong, Pili, Roberto, Elzey, Bennett D., Ratliff, Timothy L., Wan, Jun, Hu, Chang-Deng
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669631/
https://ncbi.nlm.nih.gov/pubmed/32999000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1228
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