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Copper(II) Inhibition of the SARS-CoV-2 Main Protease
In an analysis of the structural stability of the coronavirus main protease (Mpro), we identified regions of the protein that could be disabled by cobalt(III)-cation binding to histidines and cysteines [1]. Here we have extended our work to include copper(II) chelates, which we have docked to HIS 41...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | ChemRxiv |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
ChemRxiv
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7668746/ https://ncbi.nlm.nih.gov/pubmed/33200118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26434/chemrxiv.12673436 |
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