Coagulation factor VIII, white matter hyperintensities and cognitive function: Results from the Cardiovascular Health Study

OBJECTIVE: To investigate the relationship between high FVIII clotting activity (FVIII:C), MRI-defined white matter hyperintensities (WMH) and cognitive function over time. METHODS: Data from the population-based Cardiovascular Health Study (n = 5,888, aged ≥65) were used. FVIII:C was measured in bl...

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Veröffentlicht in:PLoS One
Hauptverfasser: Rohmann, Jessica L., Longstreth, W. T., Cushman, Mary, Fitzpatrick, Annette L., Heckbert, Susan R., Rice, Kenneth, Rosendaal, Frits R., Sitlani, Colleen M., Psaty, Bruce M., Siegerink, Bob
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668572/
https://ncbi.nlm.nih.gov/pubmed/33196677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242062
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