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Pathological complete response to neoadjuvant trastuzumab and pertuzumab therapy is related to human epidermal growth factor receptor 2 (HER2) amplification level in HER2-amplified breast cancer

The human epidermal growth factor receptor 2 (HER2) is amplified in approximately 20% of breast cancers, and HER2 receptor targeting therapy is associated with a significant improvement in disease-free and overall survival. In several clinical trials, the pathologic complete response (pCR) rate was...

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Foilsithe in:Medicine (Baltimore)
Main Authors: Choi, Jin Hyuk, Jeon, Chang Wan, Kim, Young Ok, Jung, Sungui
Formáid: Artigo
Teanga:Inglês
Foilsithe: Lippincott Williams & Wilkins 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668516/
https://ncbi.nlm.nih.gov/pubmed/33181670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000023053
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