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In-vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway

STUDY QUESTION: What is the role of the Hippo and PI3K/Akt pathway in follicles during ovarian tissue culture in tissue derived from oncological patients and transgender men? SUMMARY ANSWER: Results highlight a Hippo pathway driven primordial follicle activation in vitro, predominantly from Day 0 to...

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Detalhes bibliográficos
Publicado no:Hum Reprod Open
Main Authors: De Roo, C, Lierman, S, Tilleman, K, De Sutter, P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668399/
https://ncbi.nlm.nih.gov/pubmed/33225076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hropen/hoaa048
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