Efficacy and safety of early treatment with sarilumab in hospitalised adults with COVID-19 presenting cytokine release syndrome (SARICOR STUDY): protocol of a phase II, open-label, randomised, multicentre, controlled clinical trial

INTRODUCTION: About 25% of patients with COVID-19 develop acute respiratory distress syndrome (ARDS) associated with a high release of pro-inflammatory cytokines such as interleukin-6 (IL-6). The aim of the SARICOR study is to demonstrate that early administration of sarilumab (an IL-6 receptor inhi...

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Dades bibliogràfiques
Publicat a:BMJ Open
Autors principals: León López, Rafael, Fernández, Sheila Cárcel, Limia Pérez, Laura, Romero Palacios, Alberto, Fernández-Roldán, María Concepción, Aguilar Alonso, Eduardo, Pérez Camacho, Inés, Rodriguez-Baño, Jesús, Merchante, Nicolás, Olalla, Julián, Esteban-Moreno, M Ángeles, Santos, Marta, Luque-Pineda, Antonio, Torre-Cisneros, Julian
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Infectious Diseases
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668373/
https://ncbi.nlm.nih.gov/pubmed/33191263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-039951
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