Hierarchical natural move Monte Carlo refines flexible RNA structures into cryo-EM densities

Ribonucleic acids (RNAs) play essential roles in living cells. Many of them fold into defined three-dimensional (3D) structures to perform functions. Recent advances in single-particle cryo-electron microscopy (cryo-EM) have enabled structure determinations of RNA to atomic resolutions. However, mos...

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Bibliographic Details
Published in:RNA
Main Authors: Chang, Jeng-Yih, Cui, Zhicheng, Yang, Kailu, Huang, Jianhua, Minary, Peter, Zhang, Junjie
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
Subjects:
Bioinformatics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668250/
https://ncbi.nlm.nih.gov/pubmed/32826323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071100.119
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