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Resolution of polycistronic RNA by SL2 trans-splicing is a widely conserved nematode trait

Spliced leader trans-splicing is essential for the processing and translation of polycistronic RNAs generated by eukaryotic operons. In C. elegans, a specialized spliced leader, SL2, provides the 5′ end for uncapped pre-mRNAs derived from polycistronic RNAs. Studies of other nematodes suggested that...

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Pubblicato in:RNA
Autori principali: Wenzel, Marius, Johnston, Christopher, Müller, Berndt, Pettitt, Jonathan, Connolly, Bernadette
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668243/
https://ncbi.nlm.nih.gov/pubmed/32887788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.076414.120
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