Metformin promotes susceptibility to experimental Leishmania braziliensis infection

BACKGROUND: Metformin (MET) is a hypoglycemic drug used for the treatment of diabetes, despite interference in host immunity against microorganisms. Cutaneous infection caused by pathogens such as Leishmania braziliensis (Lb), the agent responsible for cutaneous leishmaniasis (CL) in Brazil, represe...

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Vydáno v:Mem Inst Oswaldo Cruz
Hlavní autoři: Lima, Filipe Rocha, Ferreira, Lais de Melo, Malta, Tainá Alves, Bonyek-Silva, Icaro, Santos, Reinan Lima, Tavares, Natália Machado, de Carvalho Filho, Edgar Marcelino, Arruda, Sérgio
Médium: Artigo
Jazyk:Inglês
Vydáno: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668079/
https://ncbi.nlm.nih.gov/pubmed/33206822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760200272
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