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Lysine acetylation regulates the activity of nuclear Pif1

In Saccharomyces cerevisiae, the Pif1 helicase functions in both nuclear and mitochondrial DNA replication and repair processes, preferentially unwinding RNA:DNA hybrids and resolving G-quadruplex structures. We sought to determine how the various activities of Pif1 are regulated in vivo. Here, we r...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ononye, Onyekachi E., Sausen, Christopher W., Balakrishnan, Lata, Bochman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667978/
https://ncbi.nlm.nih.gov/pubmed/32878983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015164
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