The human mitochondrial enzyme BCO2 exhibits catalytic activity toward carotenoids and apocarotenoids

The enzyme β-carotene oxygenase 2 (BCO2) converts carotenoids into more polar metabolites. Studies in mammals, fish, and birds revealed that BCO2 controls carotenoid homeostasis and is involved in the pathway for vitamin A production. However, it is controversial whether BCO2 function is conserved i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Thomas, Linda D., Bandara, Sepalika, Parmar, Vipulkumar M., Srinivasagan, Ramkumar, Khadka, Nimesh, Golczak, Marcin, Kiser, Philip D., von Lintig, Johannes
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Lipids
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667965/
https://ncbi.nlm.nih.gov/pubmed/32873706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015515
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