Targeting Epstein-Barr virus oncoprotein LMP1-mediated high oxidative stress suppresses EBV lytic reactivation and sensitizes tumors to radiation therapy

Generating oxidative stress is a critical mechanism by which host cells defend against infection by pathogenic microorganisms. Radiation resistance is a critical problem in radiotherapy against cancer. Epstein-Barr virus (EBV) is a cancer-causing virus and its reactivation plays an important role in...

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Publicado no:Theranostics
Main Authors: Hu, Jianmin, Li, Yueshuo, Li, Hongde, Shi, Feng, Xie, Longlong, Zhao, Lin, Tang, Min, Luo, Xiangjian, Jia, Weihua, Fan, Jia, Zhou, Jian, Gao, Qiang, Qiu, Shuangjian, Wu, Weizhong, Zhang, Xin, Liao, Weihua, Bode, Ann M., Cao, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667690/
https://ncbi.nlm.nih.gov/pubmed/33204320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46006
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