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Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli

Emerging evidence is revealing that microRNAs (miRNAs) play essential roles in mechanosensing for regulating osteogenesis. However, no mechanoresponsive miRNAs have been identified in human bone specimens. Methods: Bedridden and aged patients, hindlimb unloaded and aged mice, and Random Positioning...

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Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Chen, Zhihao, Zhao, Fan, Liang, Chao, Hu, Lifang, Li, Dijie, Zhang, Yan, Yin, Chong, Chen, Lei, Wang, Luyao, Lin, Xiao, Su, Peihong, Ma, Jianhua, Yang, Chaofei, Tian, Ye, Zhang, Wenjuan, Li, Yu, Peng, Songlin, Chen, Weiyi, Zhang, Ge, Qian, Airong
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667683/
https://ncbi.nlm.nih.gov/pubmed/33204341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.53009
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