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Emerging Chromatography-Free High-Throughput Mass Spectrometry Technologies for Generating Hits and Leads

[Image: see text] Mass spectrometry (MS) detection can offer unmatched selectivity and sensitivity. The use of MS without chromatography greatly increases the throughput, making it suitable for high throughput screening. However, the trade-offs of direct MS detection need to be carefully evaluated a...

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Detalles Bibliográficos
Publicado en:ACS Med Chem Lett
Main Authors: Pu, Fan, Elsen, Nathaniel L., Williams, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667647/
https://ncbi.nlm.nih.gov/pubmed/33214819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00314
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