The overexpression of AUF1 in colorectal cancer predicts a poor prognosis and promotes cancer progression by activating ERK and AKT pathways

BACKGROUND: AUF1 is one of the AU‐rich binding proteins, which promotes rapid ARE‐mRNA degradation. Recently, it has been reported that AUF1 is involved in regulating the antioxidant system because of its capacity to bind specifically to RNA containing oxidized bases and degrade oxidized RNA. Many a...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Tian, Xin‐Yuan, Li, Jin, Liu, Teng‐Hui, Li, Dan‐Ni, Wang, Jing‐Jing, Zhang, He, Deng, Zhou‐Lu, Chen, Fu‐Jun, Cai, Jian‐Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666750/
https://ncbi.nlm.nih.gov/pubmed/33016643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3464
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