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Integrated genomic analysis identifies a genetic mutation model predicting response to immune checkpoint inhibitors in melanoma

Several biomarkers such as tumor mutation burden (TMB), neoantigen load (NAL), programmed cell‐death receptor 1 ligand (PD‐L1) expression, and lactate dehydrogenase (LDH) have been developed for predicting response to immune checkpoint inhibitors (ICIs) in melanoma. However, some limitations includi...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Jiang, Junjie, Ding, Yongfeng, Wu, Mengjie, Chen, Yanyan, Lyu, Xiadong, Lu, Jun, Wang, Haiyong, Teng, Lisong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666739/
https://ncbi.nlm.nih.gov/pubmed/32969604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3481
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