Gain of Function of Ion Channel TRPV1 Exacerbates Experimental Colitis by Promoting Dendritic Cell Activation

Dysregulated mucosal immunity plays an essential role in the pathophysiology of inflammatory bowel disease (IBD). Transient receptor potential vanilloid 1 (TRPV1) is a Ca(2+)-permeable ion channel that is implicated in modulating immune responses. However, its role in the pathogenesis of intestinal...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Duo, Lina, Wu, Ting, Ke, Ziliang, Hu, Linghan, Wang, Chaohui, Teng, Guigen, Zhang, Wei, Wang, Weihong, Ge, Qing, Yang, Yong, Dai, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666365/
https://ncbi.nlm.nih.gov/pubmed/33251043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.006
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