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The Arf-GEF Steppke promotes F-actin accumulation, cell protrusions and tissue sealing during Drosophila dorsal closure

Cytohesin Arf-GEFs promote actin polymerization and protrusions of cultured cells, whereas the Drosophila cytohesin, Steppke, antagonizes actomyosin networks in several developmental contexts. To reconcile these findings, we analyzed epidermal leading edge actin networks during Drosophila embryo dor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: West, Junior J., Harris, Tony J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665897/
https://ncbi.nlm.nih.gov/pubmed/33186390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239357
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