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A path towards SARS-CoV-2 attenuation: metabolic pressure on CTP synthesis rules the virus evolution
In the context of the COVID-19 pandemic, we describe here the singular metabolic background that constrains enveloped RNA viruses to evolve towards likely attenuation in the long term, possibly after a step of increased pathogenicity. Cytidine triphosphate (CTP) is at the crossroad of the processes...
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| Publicado no: | Genome Biol Evol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7665462/ https://ncbi.nlm.nih.gov/pubmed/33125064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evaa229 |
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