Baseline CD44v6-positive circulating tumor cells to predict first-line treatment failure in patients with metastatic colorectal cancer

CD44v6, the CD44 isoform mostly involved in cancer cell migration and invasion, has been identified as a functional biomarker and therapeutic target in colon cancer stem cells. We here provide evidence that baseline CD44v6-positive CTC predict treatment failure in patients with metastatic colorectal...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Nicolazzo, Chiara, Loreni, Flavia, Caponnetto, Salvatore, Magri, Valentina, Vestri, Anna Rita, Zamarchi, Rita, Gradilone, Angela, Facchinetti, Antonella, Rossi, Elisabetta, Cortesi, Enrico, Gazzaniga, Paola
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665234/
https://ncbi.nlm.nih.gov/pubmed/33227095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27794
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