Knockdown lncRNA NEAT1 regulates the activation of microglia and reduces AKT signaling and neuronal apoptosis after cerebral ischemic reperfusion

Acute cerebral ischaemia may lead to serious consequences, including brain injury caused by uncontrolled reperfusion, which occurs when circulation is re-established. The long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) plays an important role in the immune system. However...

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Pubblicato in:Sci Rep
Autori principali: Ni, Xunran, Su, Qian, Xia, Wenbo, Zhang, Yanli, Jia, Kejuan, Su, Zhiqiang, Li, Guozhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665206/
https://ncbi.nlm.nih.gov/pubmed/33184298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71411-1
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