Plasma metabolomics supports the use of long-duration cardiac arrest rodent model to study human disease by demonstrating similar metabolic alterations

Cardiac arrest (CA) is a leading cause of death and there is a necessity for animal models that accurately represent human injury severity. We evaluated a rat model of severe CA injury by comparing plasma metabolic alterations to human patients. Plasma was obtained from adult human control and CA pa...

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Vydáno v:Sci Rep
Hlavní autoři: Shoaib, Muhammad, Choudhary, Rishabh C., Choi, Jaewoo, Kim, Nancy, Hayashida, Kei, Yagi, Tsukasa, Yin, Tai, Nishikimi, Mitsuaki, Stevens, Jan F., Becker, Lance B., Kim, Junhwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665036/
https://ncbi.nlm.nih.gov/pubmed/33184308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76401-x
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