Nalaganje...
Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus
Background: Prioritizing tag-SNPs carried on extended risk haplotypes at susceptibility loci for common disease is a challenge. Methods: We utilized trans-ancestral exclusion mapping to reduce risk haplotypes at IKZF1 and IKZF3 identified in multiple ancestries from SLE GWAS and ImmunoChip datasets....
Shranjeno v:
| izdano v: | Int J Mol Sci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2020
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7664943/ https://ncbi.nlm.nih.gov/pubmed/33182226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218383 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|