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Adsorption of Chiral [5]-Aza[5]helicenes on DNA Can Modify Its Hydrophilicity and Affect Its Chiral Architecture: A Molecular Dynamics Study
Helicenes are interesting chiral molecules without asymmetric carbon atoms but with intrinsic chirality. Functionalized 5-Aza[5]helicenes can form non-covalent complexes with anticancer drugs and therefore be potential carriers. The paper highlights the different structural selectivity for DNA bindi...
Gorde:
Argitaratua izan da: | Materials (Basel) |
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Egile Nagusiak: | , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
MDPI
2020
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7664699/ https://ncbi.nlm.nih.gov/pubmed/33171884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma13215031 |
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