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3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro

The growth and differentiation of adipose tissue-derived stem cells (ASCs) is stimulated and regulated by the adipose tissue (AT) microenvironment. In lipedema, both inflammation and hypoxia influence the expansion and differentiation of ASCs, resulting in hypertrophic adipocytes and deposition of c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Al-Ghadban, Sara, Pursell, India A., Diaz, Zaidmara T., Herbst, Karen L., Bunnell, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664323/
https://ncbi.nlm.nih.gov/pubmed/33171717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218350
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