Chloride channel blocker IAA-94 increases myocardial infarction by reducing calcium retention capacity of the cardiac mitochondria

Indanyloxyacetic acid-94 (IAA-94), an intracellular chloride channel blocker, is shown to ablate cardioprotection rendered by ischemic preconditioning (IPC), N (6)-2-(4-aminophenyl) ethyladenosine or the PKC activator phorbol 12-myristate 13-acetate and cyclosporin A (CsA) in both ex-vivo and in-viv...

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Bibliografiske detaljer
Udgivet i:Life Sci
Main Authors: Ponnalagu, Devasena, Hussain, Ahmed Tafsirul, Thanawala, Rushi, Meka, Jahnavi, Bednarczyk, Piotr, Feng, Yansheng, Szewczyk, Adam, GururajaRao, Shubha, Bopassa, Jean C., Khan, Mahmood, Singh, Harpreet
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664129/
https://ncbi.nlm.nih.gov/pubmed/31494173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2019.116841
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