Multiomics Reveals Ectopic ATP Synthase Blockade Induces Cancer Cell Death via a lncRNA-mediated Phospho-signaling Network

The EGFR tyrosine kinase inhibitor gefitinib is commonly used for lung cancer patients. However, some patients eventually become resistant to gefitinib and develop progressive disease. Here, we indicate that ecto-ATP synthase, which ectopically translocated from mitochondrial inner membrane to plasm...

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Publicado en:Mol Cell Proteomics
Autores principales: Chang, Yi-Wen, Hsu, Chia-Lang, Tang, Cheng-Wei, Chen, Xiang-Jun, Huang, Hsuan-Cheng, Juan, Hsueh-Fen
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664121/
https://ncbi.nlm.nih.gov/pubmed/32788343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002219
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