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Glutathionylation Decreases Methyltransferase Activity of PRMT5 and Inhibits Cell Proliferation
Glutathionylation is an important posttranslational modification that protects proteins from further oxidative damage as well as influencing protein structure and activity. In the present study, we demonstrate that the cysteine-42 residue in protein arginine N-methyltransferase 5 (PRMT5) is glutathi...
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| Publicado no: | Mol Cell Proteomics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7664116/ https://ncbi.nlm.nih.gov/pubmed/32868396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002132 |
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