Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells

The role of leptin receptor (OB-R) signaling in linking pluripotency with growth and development and the consequences of dysfunctional leptin signaling on progression of metabolic disease is poorly understood. Using a global unbiased proteomics approach we report that embryonic fibroblasts (MEFs) ca...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Gupta, Manoj K., Vethe, Heidrun, Softic, Samir, Rao, Tata Nageswara, Wagh, Vilas, Shirakawa, Jun, Barsnes, Harald, Vaudel, Marc, Takatani, Tomozumi, Kahraman, Sevim, Sakaguchi, Masaji, Martinez, Rachael, Hu, Jiang, Bjørlykke, Yngvild, Raeder, Helge, Kulkarni, Rohit N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664055/
https://ncbi.nlm.nih.gov/pubmed/33125875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.10.001
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