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Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells

The role of leptin receptor (OB-R) signaling in linking pluripotency with growth and development and the consequences of dysfunctional leptin signaling on progression of metabolic disease is poorly understood. Using a global unbiased proteomics approach we report that embryonic fibroblasts (MEFs) ca...

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Bibliografiska uppgifter
I publikationen:Stem Cell Reports
Huvudupphovsmän: Gupta, Manoj K., Vethe, Heidrun, Softic, Samir, Rao, Tata Nageswara, Wagh, Vilas, Shirakawa, Jun, Barsnes, Harald, Vaudel, Marc, Takatani, Tomozumi, Kahraman, Sevim, Sakaguchi, Masaji, Martinez, Rachael, Hu, Jiang, Bjørlykke, Yngvild, Raeder, Helge, Kulkarni, Rohit N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664055/
https://ncbi.nlm.nih.gov/pubmed/33125875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.10.001
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