Bipotent Progenitors Do Not Require Androgen Receptor for Luminal Specification during Prostate Organogenesis

Androgen receptor (AR) plays a fundamental role in most aspects of adult prostate homeostasis, and anti-androgen therapy represents the cornerstone of prostate cancer treatment. However, early prostate organogenesis takes place during pre-pubertal stages when androgen levels are low, raising the pos...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Shibata, Maho, Epsi, Nusrat J., Xuan, Shouhong, Mitrofanova, Antonina, Shen, Michael M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664048/
https://ncbi.nlm.nih.gov/pubmed/33176121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.10.004
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