Targeting TGF-β-Mediated SMAD Signaling Pathway via Novel Recombinant Cytotoxin II: A Potent Protein from Naja naja oxiana Venom in Melanoma

Since the current treatments have not resulted in the desired outcomes for melanoma patients, there is a need to identify more effective medications. Together with other snake venom proteins, cytotoxin-II has shown promising results in tumoral cells. In this study, recombinant cytotoxin-II (rCTII) w...

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Pubblicato in:Molecules
Autori principali: Derakhshani, Afshin, Silvestris, Nicola, Hemmat, Nima, Asadzadeh, Zahra, Abdoli Shadbad, Mahdi, Nourbakhsh, Niloufar Sadat, Mobasheri, Leila, Vahedi, Parviz, Shahmirzaie, Morteza, Brunetti, Oronzo, Safarpour, Hossein, Baradaran, Behzad
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663949/
https://ncbi.nlm.nih.gov/pubmed/33167431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25215148
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